Giáo trình

Genetics

Science and Technology

Assignments and solutions

Tác giả: Lê Đình Lương
Assignments cover the topics discussed in the corresponding lecture sessions
VN-LEC# MIT-LEC # ASSIGNMENTs SOLUTIONS
3, 23, 29, 30, 32 1-5 Problem Set 1 (PDF) (PDF)
18, 27, 29, 30 6-9 Problem Set 2 (PDF) (PDF)
16, 20-23 11-15 Problem Set 3 (PDF) (PDF)
24, 25 16-19 Problem Set 4 (PDF) (PDF)
25-28 20-24 Problem Set 5 (PDF) (PDF)
33, 28 25-30 Problem Set 6 (PDF) (PDF)
31 31-35 Problem Set 7 (PDF) (PDF)

    A chromosome:
  • A. is composed of amino acids
  • B. is organized in the nucleus by histones
  • C. is produced from RNA
  • D. is present in 46 pairs in human cells

D. is present in 46 pairs in human cells

    Genes:
  • A. never function when they contain a mutation
  • . directly produce proteins
  • C. contain random pairings of nucleotides
  • D. all of the above
  • E. none of the above

E. none of the above

    During the process of transcription, genetic information is transferred from:
  • A. DNA to RNA
  • B. RNA to DNA
  • C. DNA to protein
  • D. Protein to RNA

A. DNA to RNA

    A mutation that __________ production of a given _________ can manifest as clinical disease.
  • A. increases/protein
  • B. decreases/mRNA
  • C. decreases/ protein
  • D. increases/mRNA
  • E. all of the above
  • F. none of the above

F. none of the above

    A mutation occurs that disrupts the normal structure and function of hemoglobin. Which of the following is true?
  • A. clinical disease will develop based on the mutation alone.
  • B. environmental factors can play a large role in the development of clinical disease.
  • C. each person with the same mutation will follow the same clinical course.
  • D. family members should be tested for this hereditary condition.

A. clinical disease will develop based on the mutation alone.

    A germline mutation ___________ while a somatic mutation _______________.
  • A. is never passed from parents to offspring // is present in all cells of one’s body
  • B. is always passed from parents to offspring // is present in all cells of one’s body
  • C. is present in all cells of one’s body // is never passed from parents to offspring
  • D. is responsible for non-hereditary cancers // is not often a direct cause of inherited disease

C. is present in all cells of one’s body // is never passed from parents to offspring

    A missense mutation
  • A. does not affect protein structure
  • B. does not affect protein function
  • C. leads to substitution of an amino acid in a new place in the protein
  • D. all of the above
  • E. none of the above

C. leads to substitution of an amino acid in a new place in the protein

    A nonsense mutation
  • A. does not affect protein structure
  • B. may not lead to clinical disease
  • C. involves an inappropriate stop codon
  • D. A and B
  • E. A and C
  • F. All of the above

C. involves an inappropriate stop codon

    A silent mutation
  • A. results in no change in protein structure/function
  • B. can sometimes lead to clinical disease
  • C. involves substitution of one amino acid for another
  • D. A and C
  • E. A and B

A. results in no change in protein structure/function

    A polymorphism is a form of mutation that leads to clinical disease.
  • True
  • Flase

False

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